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AHA cholesterol management guideline recommends evaluating patients for new-onset diabetes mellitus according to current diabetes screening guidelines.

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It is recommended that liver enzyme tests be performed before the initiation of Lipitor and if signs or symptoms of liver injury occur.

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The Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) was a double-blind, placebo-controlled study evaluating the effect of Lipitor on fatal and non-fatal coronary heart disease.

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According to the prescribing information, memory problems were reported as a side effect of Lipitor after the drug was approved and marketed.

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Using amlodipine and atorvastatin with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you.

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In animal models, LIPITOR lowers plasma cholesterol and lipoprotein levels by inhibiting HMG-CoA reductase and cholesterol synthesis in the liver and by increasing the number of hepatic LDL receptors on the cell-surface to enhance uptake and catabolism of LDL; LIPITOR also reduces LDL production and the number of LDL particles.

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